Cajun Chicken Alfredo Pasta

Featured in: Comfort Home Dishes

This dish brings together tender chicken breasts seasoned with Cajun spices, seared to juicy perfection, and combined with al dente fettuccine pasta. The sauce is a smooth blend of Velveeta and Parmesan cheeses melted into rich cream with hints of garlic and cayenne for gentle heat. Finished with fresh parsley, the result is a comforting plate combining bold Southern flavors and creamy textures. Ideal for a quick yet satisfying meal, it pairs well with crisp greens or chilled white wine.

Updated on Sun, 23 Nov 2025 14:54:00 GMT
Cajun Chicken Alfredo Fettuccine pasta: Sliced chicken sits atop creamy Velveeta sauce and fettuccine, ready to enjoy. Pin this
Cajun Chicken Alfredo Fettuccine pasta: Sliced chicken sits atop creamy Velveeta sauce and fettuccine, ready to enjoy. | recipeshood.com

A creamy, spicy pasta dish featuring tender Cajun-seasoned chicken, rich Velveeta cheese sauce, and perfectly cooked fettuccine—comfort food with a Southern twist.

A cozy dish that brings together bold Cajun flavors and creamy cheese sauce, perfect for sharing with family on a weeknight.

Ingredients

  • Chicken: 2 large boneless skinless chicken breasts 1 ½ tablespoons Cajun seasoning 1 tablespoon olive oil
  • Pasta: 12 oz (340 g) fettuccine pasta
  • Sauce: 2 tablespoons unsalted butter 2 cloves garlic minced 1 cup (240 ml) heavy cream 8 oz (225 g) Velveeta cheese cubed ½ cup (50 g) grated Parmesan cheese ½ teaspoon black pepper ¼ teaspoon cayenne pepper (optional for extra heat) Salt to taste
  • Garnish: 2 tablespoons fresh parsley chopped Extra grated Parmesan cheese (optional)

Instructions

Step 1:
Bring a large pot of salted water to a boil Cook the fettuccine according to package instructions until al dente Drain and set aside reserving ½ cup pasta water
Step 2:
While the pasta cooks pat chicken breasts dry Rub both sides with Cajun seasoning
Step 3:
In a large skillet heat olive oil over medium-high heat Add chicken and cook 5 6 minutes per side or until golden and cooked through (internal temperature 165°F/74°C) Remove chicken let rest 5 minutes then slice thinly
Step 4:
In the same skillet reduce heat to medium Add butter and garlic sauté 1 minute until fragrant
Step 5:
Stir in heavy cream and bring to a gentle simmer Add Velveeta cubes stirring often until melted and smooth
Step 6:
Add Parmesan cheese black pepper and cayenne pepper (if using) Stir until fully combined and creamy If sauce is too thick add reserved pasta water a little at a time
Step 7:
Toss cooked fettuccine in the sauce until well coated
Step 8:
Divide pasta among plates Top with sliced Cajun chicken Garnish with parsley and extra Parmesan if desired
Flavorful Cajun Chicken Alfredo Fettuccine featuring a vibrant cheesy sauce, ready to be devoured after a simple prep. Pin this
Flavorful Cajun Chicken Alfredo Fettuccine featuring a vibrant cheesy sauce, ready to be devoured after a simple prep. | recipeshood.com

My family loves gathering around this dish It always sparks great conversations and plenty of compliments

Serving Suggestions

Pairs well with a crisp green salad and a chilled Chardonnay for a complete meal

Allergen Information

Contains milk dairy wheat and chicken Those with allergies should check ingredient labels for hidden allergens

Nutritional Information

Per serving: 670 calories 32 g total fat 57 g carbohydrates 41 g protein

A steaming bowl of Cajun Chicken Alfredo Fettuccine: Tender chicken, creamy sauce, and parsley garnish, a perfect comfort meal. Pin this
A steaming bowl of Cajun Chicken Alfredo Fettuccine: Tender chicken, creamy sauce, and parsley garnish, a perfect comfort meal. | recipeshood.com

This dish is simple yet impressive making it perfect for any occasion

Frequently Asked Recipe Questions

How do I keep the chicken tender and juicy?

Pat the chicken dry and cook over medium-high heat just until golden and cooked through without overcooking to retain juiciness.

Can I adjust the spice level in the sauce?

Yes, modify the amount of cayenne pepper or Cajun seasoning to suit your preferred heat intensity.

What’s the best way to get a smooth sauce texture?

Stir the Velveeta cheese cubes into simmering cream gradually and add reserved pasta water as needed to achieve a creamy consistency.

Which pasta works best for this dish?

Fettuccine is ideal due to its wide ribbons that hold the creamy sauce well, but other long pastas like linguine can also work.

Can I prepare this dish ahead of time?

Yes, cook and slice the chicken and prepare the sauce in advance. Keep pasta separate and combine just before serving for best texture.

Cajun Chicken Alfredo Pasta

Spiced chicken and fettuccine combined in a creamy Velveeta cheese sauce for a savory Southern dish.

Prep Duration
15 min
Time to Cook
25 min
Overall Time
40 min
Created by Julia Harris


Level of Challenge Easy

Cuisine Type American (Cajun-inspired)

Servings Made 4 Number of Portions

Dietary Details None specified

What You'll Need

Chicken

01 2 large boneless, skinless chicken breasts
02 1 ½ tablespoons Cajun seasoning
03 1 tablespoon olive oil

Pasta

01 12 ounces fettuccine pasta

Sauce

01 2 tablespoons unsalted butter
02 2 cloves garlic, minced
03 1 cup heavy cream
04 8 ounces Velveeta cheese, cubed
05 ½ cup grated Parmesan cheese
06 ½ teaspoon black pepper
07 ¼ teaspoon cayenne pepper (optional)
08 Salt, to taste

Garnish

01 2 tablespoons fresh parsley, chopped
02 Extra grated Parmesan cheese (optional)

Method

Step 01

Cook pasta: Bring a large pot of salted water to a boil. Cook the fettuccine according to package instructions until al dente. Drain and reserve ½ cup of pasta water.

Step 02

Prepare chicken: Pat chicken breasts dry and rub both sides evenly with Cajun seasoning.

Step 03

Cook chicken: Heat olive oil in a large skillet over medium-high heat. Cook chicken 5 to 6 minutes per side until golden and fully cooked (internal temperature 165°F). Remove and rest for 5 minutes, then slice thinly.

Step 04

Sauté garlic: Reduce heat to medium and add butter and garlic to the same skillet. Sauté for 1 minute until fragrant.

Step 05

Prepare sauce: Stir in heavy cream and bring to a gentle simmer. Add Velveeta cubes and stir continuously until melted and smooth.

Step 06

Season sauce: Mix in Parmesan cheese, black pepper, and cayenne pepper if using. Stir until creamy. If the sauce is too thick, gradually add reserved pasta water to desired consistency.

Step 07

Combine pasta and sauce: Toss cooked fettuccine in the sauce ensuring it is fully coated.

Step 08

Serve: Divide pasta onto serving plates and top with sliced Cajun chicken. Garnish with chopped parsley and extra Parmesan cheese if desired.

Kitchen Tools Needed

  • Large pot
  • Large skillet
  • Knife and cutting board
  • Tongs or pasta fork
  • Measuring cups and spoons

Allergen Details

Review every ingredient for allergens and reach out to a professional if you're unsure.
  • Contains milk/dairy products including Velveeta, Parmesan, cream, and butter.
  • Contains wheat present in fettuccine pasta.
  • Contains poultry.
  • Check labels carefully for hidden allergens.

Nutrition Details (per portion)

Nutrition info is for reference purposes only and isn't medical advice.
  • Energy (Calories): 670
  • Fats: 32 g
  • Carbohydrates: 57 g
  • Proteins: 41 g